Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 12/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5979508 | 0.92 | PIK3CB (0.42) | PIK3CBMAPT | |
| SCHEMBL4564467 | 0.91 | PIK3CB (0.49) | PIK3CB | |
| SCHEMBL4565205 | 0.85 | PIK3CB (0.48) | PIK3CB | |
| SCHEMBL4565204 | 0.85 | PIK3CB (0.48) | PIK3CB | |
| SCHEMBL4565471 | 0.85 | PIK3CB (0.48) | PIK3CBABCB1 | |
| SCHEMBL4565470 | 0.85 | PIK3CB (0.48) | PIK3CBABCB1 | |
| SCHEMBL4565319 | 0.84 | PIK3CB (0.48) | PIK3CBABCB1 | |
| SCHEMBL4565313 | 0.84 | PIK3CB (0.48) | PIK3CBABCB1 | |
| SCHEMBL5980921 | 0.84 | SMN1; SMN2 (0.37) | PIK3CBMAPT | |
| SCHEMBL4564651 | 0.83 | PIK3CB (0.49) | PIK3CBABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062745-A1 | ALKOXY-SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-18 | — | — | WO | disclosed |