⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827253 | 1.00 | — | — | |
| SCHEMBL21827191 | 1.00 | — | — | |
| SCHEMBL14635960 | 0.82 | — | — | |
| SCHEMBL20425156 | 0.82 | — | — | |
| SCHEMBL16877073 | 0.77 | — | — | |
| SCHEMBL2012570 | 0.72 | — | — | |
| SCHEMBL23072739 | 0.71 | — | — | |
| SCHEMBL10296437 | 0.71 | — | — | |
| SCHEMBL22362306 | 0.62 | — | — | |
| SCHEMBL2040256 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284797-A1 | PYRAZOLEAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-12-06 | — | — | EP | claimed |
| US-20230382911-A1 | PYRAZOLEAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-11-30 | — | — | US | claimed |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | claimed |
| CN-107698541-A | The preparation method of 3 tetrahydrofurfuryl carbinols | 陕西启源科技发展有限责任公司 | 2018-02-16 | — | — | CN | claimed |
| CN-107382916-A | The high purity synthetic process of 3 tetrahydrofurfuryl carbinols | 成都化润药业有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-107226798-A | The new technology of 3 tetrahydrofurfuryl carbinols of synthesis is reacted by Prins | 成都化润药业有限公司 | 2017-10-03 | — | — | CN | claimed |
| CN-107141273-A | Using the new technology of the methanol of one pot process tetrahydrofuran 3 | 成都化润药业有限公司 | 2017-09-08 | — | — | CN | claimed |
| EP-2603218-B1 | QUINOLYL AMINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2016-03-02 | — | — | EP | claimed |
| EP-2566477-B1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2015-09-02 | — | — | EP | claimed |
| EP-2603218-A1 | QUINOLYL AMINES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2013-06-19 | — | — | EP | claimed |
| EP-1506185-A1 | NOVEL COMPOUNDS AND THEIR USE | Biovitrum AB (SE) | 2005-02-16 | — | — | EP | claimed |
| US-20030232814-A1 | Novel compounds and their use | BIOVITRUM AB (PUBL) (SE) | 2003-12-18 | — | — | US | claimed |
| WO-2003097636-A1 | NOVEL COMPOUNDS AND THEIR USE | BIOVITRUM AB (SE) | 2003-11-27 | — | — | WO | claimed |
| EP-0984778-B1 | NEUROPEPTIDE-Y LIGANDS | AGOURON PHARMA (US) | 2002-06-12 | — | — | EP | claimed |
| EP-0984778-A4 | NEUROPEPTIDE-Y LIGANDS | ALANEX CORP (US) | 2000-06-07 | — | — | EP | claimed |
| EP-0984778-A1 | NEUROPEPTIDE-Y LIGANDS | Alanex Corporation (US) | 2000-03-15 | — | — | EP | claimed |
| WO-1998007420-A1 | NEUROPEPTIDE-Y LIGANDS | AGOURON ACQUISITION CORP. (US) | 1998-02-26 | — | — | WO | claimed |
| US-5436262-A | Pharmacologically active derivatives of 2-(benzimidazol-2-yl)-1,3-diaminopropane | DOMPE FARMACEUTICI SPA (IT) | 1995-07-25 | — | — | US | claimed |
| EP-0630889-A1 | Pharmacologically active derivatives of 2-(benzimidazol-2-yl)-1,3-diaminopropane | DOMPE' FARMACEUTICI S.p.A. (IT) | 1994-12-28 | — | — | EP | claimed |
| WO-1993012113-A1 | 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY | THE UPJOHN COMPANY (US) | 1993-06-24 | — | — | WO | claimed |