⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889222 | 0.88 | — | — | |
| SCHEMBL10816986 | 0.82 | — | — | |
| SCHEMBL606699 | 0.76 | — | — | |
| SCHEMBL16382053 | 0.76 | — | — | |
| SCHEMBL18789653 | 0.76 | — | — | |
| SCHEMBL491178 | 0.74 | — | — | |
| SCHEMBL19302252 | 0.71 | — | — | |
| SCHEMBL724555 | 0.71 | — | — | |
| SCHEMBL18013645 | 0.71 | — | — | |
| SCHEMBL5584073 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60184065-A | — | — | None | — | — | JP | disclosed |
| US-20230339947-A1 | USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS | Madera Therapeutics, LLC | 2023-10-26 | — | — | US | disclosed |
| EP-2540697-B1 | METHOD FOR PRODUCING DIARYL CARBONATE | ASAHI CHEMICAL IND (JP) | 2022-04-20 | — | — | EP | disclosed |
| US-20210238192-A1 | VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. | 2021-08-05 | — | — | US | disclosed |
| US-20170065541-A1 | SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMINOTHIOL RADIOPROTECTORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-03-09 | — | — | US | disclosed |
| US-20170065541-A1 | SYNTHESIS AND GROWTH REGULATORY ACTIVITY OF A PROTOTYPE MEMBER OF A NEW FAMILY OF AMINOTHIOL RADIOPROTECTORS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-03-09 | — | — | US | disclosed |
| US-9458100-B2 | Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458100-B2 | Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9193682-B2 | Synthesis of trithiocarbonates and allyl sulfides and their application into advances in covalent adaptable networks | Fenoli, Christopher R. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150183779-A1 | SOLID STATE FORM OF VEMURAFENIB CHOLINE SALT | RATIOPHARM GMBH (DE) | 2015-07-02 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | disclosed |
| EP-1084110-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999055677-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-04 | — | — | WO | disclosed |
| US-5113000-A | Multifunctional, sealers for semiconductors, improved adhesion | TOSHIBA SILICONE CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| JP-S60184065-A | 2-METHYLENE-1,3-PROPANEDIAMINE COMPOUND | DAICEL CHEM IND LTD | 1985-09-19 | — | — | JP | disclosed |