⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023898 | 0.72 | — | — | |
| SCHEMBL18635772 | 0.72 | — | — | |
| SCHEMBL12759217 | 0.69 | — | — | |
| SCHEMBL18756528 | 0.69 | — | — | |
| SCHEMBL8099258 | 0.69 | — | — | |
| SCHEMBL5590122 | 0.69 | — | — | |
| SCHEMBL12227948 | 0.69 | — | — | |
| SCHEMBL5590128 | 0.69 | — | — | |
| SCHEMBL13381508 | 0.69 | — | — | |
| SCHEMBL3603565 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1093563-A | — | — | None | — | — | JP | disclosed |
| JP-2108654-A | — | — | None | — | — | JP | disclosed |
| CN-102885708-B | Composition for external use | OTSUKA PHARMA CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| US-4959493-A | CENTRAL NERVOUS SYSTEM DISORDERS | SUNTORY LIMITED (JP) | 1990-09-25 | — | — | US | disclosed |
| JP-H02108654-A | (2R,3S,4S)-ALPHA-(CARBOXYCYCLOPROPYL)GLYCINE | SUNTORY LTD | 1990-04-20 | — | — | JP | disclosed |
| JP-H0193563-A | CARBOXYCYCLOPROPYLGLYCINE AND PRODUCTION THEREOF | SUNTORY LTD | 1989-04-12 | — | — | JP | disclosed |