⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066472 | 0.77 | — | — | |
| SCHEMBL314943 | 0.77 | — | — | |
| SCHEMBL1509779 | 0.72 | — | — | |
| SCHEMBL3139543 | 0.72 | — | — | |
| SCHEMBL16295693 | 0.72 | — | — | |
| SCHEMBL23451722 | 0.71 | — | — | |
| SCHEMBL9728681 | 0.67 | — | — | |
| SCHEMBL6434952 | 0.67 | — | — | |
| SCHEMBL5665816 | 0.67 | — | — | |
| SCHEMBL352421 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078406-B2 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, L.L.C. (US) | 2006-07-18 | — | — | US | disclosed |
| US-20040248851-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | Life Technologies Corporation | 2004-12-09 | — | — | US | disclosed |
| US-6815445-B2 | FOR USE AS FLUORESCENCE DYES AND PROBES | Life Technologies Corporation | 2004-11-09 | — | — | US | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030105111-A1 | Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-06-05 | — | — | US | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| CN-1144258-A | Method of soil decontamination | BASF AG (DE) | 1997-03-05 | — | — | CN | disclosed |
| EP-0618912-B1 | METHOD OF PRODUCING TETRAHYDRO-3,5-DIMETHYL-1,3,5-THIADIAZIN-2-THION POWDER SUBSTANTIALLY FREE OF DUST FINES | BASF AG (DE) | 1996-11-20 | — | — | EP | disclosed |
| US-5495017-A | Preparation of substantially dust-free tetrahydro-3,5-dimethyl-1,3,5-thiadiazine-2-thione granules | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-27 | — | — | US | disclosed |
| EP-0618912-A1 | METHOD OF PRODUCING TETRAHYDRO-3,5-DIMETHYL-1,3,5-THIADIAZIN-2-THION POWDER SUBSTANTIALLY FREE OF DUST FINES. | BASF AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013085-A1 | METHOD OF PRODUCING TETRAHYDRO-3,5-DIMETHYL-1,3,5-THIADIAZIN-2-THION POWDER SUBSTANTIALLY FREE OF DUST FINES | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |