Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | VNN1 | O95497 | 4/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014963 | 0.95 | F10 (0.51) | F10F2VNN1CCR1CNR2 | |
| SCHEMBL3451230 | 0.90 | F10 (0.49) | F10F2VNN1CCR1CNR2 | |
| SCHEMBL3449100 | 0.88 | F10 (0.47) | F10F2VNN1CCR1CNR2 | |
| SCHEMBL3451241 | 0.88 | F10 (0.47) | F10F2VNN1CCR1CNR2 | |
| SCHEMBL3450382 | 0.85 | F10 (0.45) | F10F2VNN1 | |
| SCHEMBL3450333 | 0.85 | F10 (0.49) | F10F2CCR1EGFRCSF1R | |
| SCHEMBL6015019 | 0.84 | F10 (0.53) | F10F2CCR1 | |
| SCHEMBL6015095 | 0.83 | F10 (0.52) | F10F2JAK2JAK1JAK3 | |
| SCHEMBL3448607 | 0.82 | F10 (0.43) | F10F2VNN1CCR1CNR2 | |
| SCHEMBL6015076 | 0.82 | F10 (0.42) | F10F2CCR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |