Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | YAP1 | P46937 | 11/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451037 | 0.93 | F10 (0.51) | F10F2 | |
| SCHEMBL6015060 | 0.93 | F10 (0.51) | F10F2 | |
| SCHEMBL3450764 | 0.90 | F10 (0.48) | F10F2CACNA1B | |
| SCHEMBL6015139 | 0.86 | F10 (0.47) | F10F2YAP1 | |
| SCHEMBL6015110 | 0.85 | F10 (0.48) | F10F2ACE | |
| SCHEMBL3449486 | 0.85 | F10 (0.45) | F10F2YAP1CACNA1B | |
| SCHEMBL3448801 | 0.81 | F10 (0.51) | F10F2 | |
| SCHEMBL3449017 | 0.81 | F10 (0.51) | F10F2 | |
| SCHEMBL3449287 | 0.81 | F10 (0.51) | F10F2 | |
| SCHEMBL6015113 | 0.81 | F10 (0.52) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |