Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448613 | 0.92 | CCR1 (0.37) | CCR1CNR2CTSKITGB3ITGA2B | |
| SCHEMBL3449036 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL3448493 | 0.85 | CCR1 (0.41) | CCR1KDM4EALDH1A1GAATSHR | |
| SCHEMBL6014965 | 0.85 | CCR1 (0.39) | CCR1CNR2CTSK | |
| SCHEMBL3448992 | 0.83 | — | — | |
| SCHEMBL6015020 | 0.81 | CCR1 (0.36) | CCR1CTSK | |
| SCHEMBL3451234 | 0.80 | CCR1 (0.36) | CCR1 | |
| SCHEMBL3449185 | 0.79 | CCR1 (0.34) | CCR1CNR2 | |
| SCHEMBL3448425 | 0.79 | CCR1 (0.41) | CCR1ALDH1A1 | |
| SCHEMBL6015058 | 0.79 | CCR1 (0.33) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |