Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 20/20 | 0.57 |
| ▸ | OXTR | P30559 | 13/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857324 | 0.88 | AVPR1A (0.58) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL5552234 | 0.85 | AVPR1A (0.66) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2131016 | 0.82 | AVPR1A (0.64) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2131571 | 0.80 | AVPR1A (0.70) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2862621 | 0.79 | AVPR1A (0.62) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2863069 | 0.79 | AVPR1A (0.62) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL4838025 | 0.79 | AVPR1A (0.81) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18917228 | 0.78 | AVPR1A (0.67) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2856323 | 0.78 | AVPR1A (0.63) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2859717 | 0.78 | AVPR1A (0.59) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632494-A1 | Vasopressin v1a antagonists | FERRING B.V. (NL) | 2006-03-08 | — | — | EP | claimed |