Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL654520 | 0.82 | SYK (0.74) | SYKAURKA | |
| R-112 SCHEMBL29360016 | 0.79 | SYK (1.00) | SYKAURKA | |
| R-112 SCHEMBL655935 | 0.79 | SYK (1.00) | SYKAURKA | |
| R-112 SCHEMBL31294216 | 0.79 | SYK (1.00) | SYKAURKA | |
| SCHEMBL656378 | 0.79 | SYK (0.67) | SYKAURKA | |
| SCHEMBL655791 | 0.79 | SYK (0.67) | SYKAURKA | |
| SCHEMBL655691 | 0.79 | SYK (0.79) | SYKAURKA | |
| SCHEMBL656111 | 0.78 | SYK (0.76) | SYKAURKA | |
| SCHEMBL655902 | 0.78 | SYK (0.77) | SYKAURKA | |
| SCHEMBL12567975 | 0.75 | SYK (0.85) | SYKAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471915-A4 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS INC (US) | 2006-02-15 | — | — | EP | disclosed |
| EP-1471915-A2 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | Rigel Pharmaceuticals, Inc. (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003063794-A2 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2003-08-07 | — | — | WO | disclosed |