Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 18/20 | 0.80 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.78 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016585 | 1.00 | CDK1 (0.80) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL13046767 | 0.89 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL13046771 | 0.88 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL1217356 | 0.88 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3690226 | 0.88 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3690229 | 0.88 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL13046769 | 0.87 | CDK1 (0.75) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL13046772 | 0.86 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3694417 | 0.85 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3694825 | 0.85 | CDK1 (1.00) | CDK1CDK5CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244668-B1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE THEREOF | UNIVERSITAIRE INSTELLING ANTWE (BE) | 2006-04-05 | — | — | EP | claimed |