Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | PARP1 | P09874 | 6/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792281 | 0.89 | PDE4A (0.40) | F10PARP1PDE4APDE4BPDE4C | |
| SCHEMBL1380869 | 0.87 | F10 (0.55) | F10PARP1F2 | |
| SCHEMBL3795899 | 0.79 | C5AR1 (0.38) | F10PARP1 | |
| SCHEMBL1379748 | 0.78 | F10 (0.57) | F10PARP1F2 | |
| SCHEMBL1380973 | 0.76 | F10 (0.62) | F10PARP1F2 | |
| SCHEMBL3794629 | 0.74 | F10 (0.61) | F10PARP1F2 | |
| SCHEMBL6016927 | 0.71 | F10 (0.55) | F10F2 | |
| SCHEMBL6016887 | 0.70 | F10 (0.50) | F10F2 | |
| SCHEMBL6016953 | 0.68 | F10 (0.55) | F10F2 | |
| SCHEMBL6016954 | 0.67 | F10 (0.55) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |