Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | FAP | Q12884 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427243 | 0.88 | DPP4 (0.79) | DPP4CYP3A4FAP | |
| SCHEMBL3427620 | 0.86 | DPP4 (0.66) | DPP4CYP3A4FAP | |
| SCHEMBL3427616 | 0.86 | DPP4 (0.66) | DPP4CYP3A4FAP | |
| SCHEMBL3427644 | 0.85 | DPP4 (0.66) | DPP4CYP3A4FAP | |
| SCHEMBL3427638 | 0.85 | DPP4 (0.66) | DPP4CYP3A4FAP | |
| SCHEMBL3424954 | 0.85 | DPP4 (0.67) | DPP4CYP3A4FAP | |
| SCHEMBL3424957 | 0.85 | DPP4 (0.67) | DPP4CYP3A4FAP | |
| SCHEMBL3427975 | 0.82 | DPP4 (0.70) | DPP4CYP3A4FAP | |
| SCHEMBL3427972 | 0.82 | DPP4 (0.70) | DPP4CYP3A4FAP | |
| SCHEMBL3428451 | 0.80 | DPP4 (0.72) | DPP4CYP3A4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608317-A4 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1608317-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda San Diego, Inc. (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004087053-A2 | DIPEPTIDYL PEPTIDASE INHIBITORS | SYRRX, INC. (US) | 2004-10-14 | — | — | WO | disclosed |