Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016951 | 0.95 | F10 (0.46) | F10F2KLK1 | |
| SCHEMBL6016940 | 0.90 | F10 (0.44) | F10F2KLK1 | |
| SCHEMBL3368877 | 0.80 | F10 (0.46) | F10F2KLK1 | |
| SCHEMBL6016927 | 0.78 | F10 (0.55) | F10F2KLK1 | |
| SCHEMBL3371016 | 0.77 | F10 (0.48) | F10F2KLK1 | |
| SCHEMBL6254590 | 0.76 | F10 (0.45) | F10F2KLK1 | |
| SCHEMBL6252807 | 0.76 | F10 (0.45) | F10F2KLK1 | |
| SCHEMBL3370000 | 0.75 | F10 (0.42) | F10F2KLK1 | |
| SCHEMBL6016943 | 0.74 | F10 (0.57) | F10F2KLK1 | |
| SCHEMBL6252590 | 0.74 | F10 (0.45) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |