Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829172 | 0.96 | APP (0.41) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL4828965 | 0.87 | EHMT2 (0.49) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL4829422 | 0.82 | BCL6 (0.49) | CTSSCTSKBCL6ALDH1A1KDM4E | |
| SCHEMBL5030894 | 0.80 | EHMT2 (0.47) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL4838893 | 0.78 | EHMT2 (0.53) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL14294097 | 0.77 | EHMT2 (0.49) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL4839842 | 0.77 | EHMT2 (0.43) | EHMT2EHMT1PDE5ABCL6ALDH1A1 | |
| SCHEMBL4838191 | 0.77 | EHMT2 (0.49) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL14533520 | 0.75 | EHMT2 (0.47) | APPBCHEACHEEHMT2EHMT1 | |
| SCHEMBL5032287 | 0.75 | KDM4E (0.38) | EHMT2EHMT1PDE5AKDM1ABCL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |