Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016959 | 0.96 | F10 (0.49) | F10F2NPC1USP2ALDH1A1 | |
| SCHEMBL3371303 | 0.94 | F10 (0.56) | F10F2NPC1USP2ALDH1A1 | |
| SCHEMBL6016807 | 0.89 | F10 (0.56) | F10F2 | |
| SCHEMBL1379952 | 0.89 | F10 (0.56) | F10F2 | |
| SCHEMBL3372431 | 0.86 | F10 (0.54) | F10F2ALDH1A1 | |
| SCHEMBL3367570 | 0.84 | F10 (0.63) | F10F2 | |
| SCHEMBL3370081 | 0.81 | F10 (0.54) | F10F2ALDH1A1 | |
| SCHEMBL3369596 | 0.81 | F10 (0.65) | F10F2 | |
| SCHEMBL6016900 | 0.81 | F10 (0.57) | F10F2 | |
| SCHEMBL1382269 | 0.81 | F10 (0.57) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |