Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 7/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032287 | 0.84 | KDM4E (0.38) | GALR1KMT2AEHMT2EHMT1KDM1A | |
| SCHEMBL4839842 | 0.76 | EHMT2 (0.43) | GALR1KMT2AEHMT2EHMT1 | |
| SCHEMBL4837222 | 0.72 | CCR4 (0.43) | GALR1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL5031282 | 0.71 | GALR1 (0.44) | HTR2AHTR2CHTR2BGALR1TUBB4A | |
| SCHEMBL5549939 | 0.71 | EHMT2 (0.39) | HTR2AHTR2CHTR2BGALR1KMT2A | |
| SCHEMBL4836743 | 0.71 | CCR4 (0.42) | GALR1KMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL4839396 | 0.70 | GALR1 (0.47) | GALR1 | |
| SCHEMBL5424915 | 0.70 | EHMT2 (0.39) | HTR2AGALR1KMT2ACDK9CCNT1 | |
| SCHEMBL6863750 | 0.70 | EHMT2 (0.46) | GALR1EHMT2EHMT1 | |
| SCHEMBL4837987 | 0.70 | EHMT2 (0.50) | KMT2AEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |