Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 7/20 | 0.48 |
| ▸ | TGM1 | P22735 | 7/20 | 0.48 |
| ▸ | F13A1 | P00488 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929898 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL388349 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL6017217 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL3933852 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL2532572 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL30400669 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL7399328 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL14514898 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19HTT | |
| SCHEMBL458394 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 | |
| SCHEMBL375302 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9ACYP2C19TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720874-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Bioaxone Therapeutique Inc. (CA) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005080394-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | BIOAXONE THERAPEUTIQUE INC. (CA) | 2005-09-01 | — | — | WO | disclosed |