Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.58 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407179 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9318472 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9240001 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5866494 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9239737 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL13987904 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9235626 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6017545 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL5866522 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9318688 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464058-B1 | FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1995-06-14 | — | — | EP | claimed |
| EP-1723215-A2 | LIQUID CRYSTAL MATERIALS HAVING SILYL TAIL GROUPS | Displaytech, Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20050189514-A1 | Liquid crystal materials having silyl tail groups | DISPLAYTECH, INC. | 2005-09-01 | — | — | US | disclosed |
| WO-2005077101-A2 | LIQUID CRYSTAL MATERIALS HAVING SILYL TAIL GROUPS | DISPLAYTECH, INC. (US) | 2005-08-25 | — | — | WO | disclosed |
| US-5594575-A | Ferroelectric liquid-crystal systems having three or more chiral additives with different signs of the helical twist in the cholesteric phase | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5439612-A | Ferroelectric switches, displaying | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-08 | — | — | US | disclosed |
| EP-0464058-B1 | FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |
| EP-0318423-B1 | Liquid crystalline cyclopropyl alkyl or alkenylhetero rings, process for their preparation and their use in liquid-crystal mixtures | HOECHST AG (DE) | 1995-02-01 | — | — | EP | disclosed |
| US-5384070-A | Use of optically active tetrahydrofuran-2-carboxylic acid esters as dopants in liquid-crystal mixtures, liquid-crystal mixtures containing same and novel optically active tetrahydrofuran-2-carboxylic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-24 | — | — | US | disclosed |
| WO-1993020069-A1 | CHIRAL OXIRANE DERIVATIVES AND THEIR USE AS DOPING AGENTS IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-14 | — | — | WO | disclosed |
| US-5200521-A | Ferroelectricity; electrooptical switching and display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
| EP-0464058-A1 | FERROELECTRIC LIQUID CRYSTAL MIXTURES. | HOECHST AG (DE) | 1992-01-08 | — | — | EP | disclosed |
| EP-0464073-A1 | FERROELECTRIC LIQUID CRYSTAL SYSTEMS WITH HIGH SPONTANEOUS POLARIZATION AND GOOD ORIENTATION PROPERTIES. | HOECHST AG (DE) | 1992-01-08 | — | — | EP | disclosed |
| US-5071589-A | Additionally contain dope | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| WO-1990011335-A1 | FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| WO-1990011547-A1 | FERROELECTRIC LIQUID CRYSTAL SYSTEMS WITH HIGH SPONTANEOUS POLARIZATION AND GOOD ORIENTATION PROPERTIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| WO-1990011336-A1 | LIQUID CRYSTAL MIXTURES, IN PARTICULAR FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-04 | — | — | WO | disclosed |
| EP-0355008-A2 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-21 | — | — | EP | disclosed |
| EP-0307880-A2 | Ferroelectric liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |