Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565179 | 0.92 | EGFR (0.56) | EGFRERBB2ERBB4 | |
| SCHEMBL5564542 | 0.84 | EGFR (0.58) | EGFRERBB2ERBB4 | |
| SCHEMBL5564723 | 0.84 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL5569519 | 0.83 | EGFR (0.64) | EGFRERBB2ERBB4 | |
| SCHEMBL5568830 | 0.83 | ERBB2 (0.51) | EGFRERBB2ERBB4 | |
| SCHEMBL5567844 | 0.80 | ERBB2 (0.58) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL5564704 | 0.80 | ERBB2 (0.57) | EGFRERBB2 | |
| SCHEMBL5567987 | 0.79 | EGFR (0.63) | EGFRERBB2 | |
| SCHEMBL5568052 | 0.78 | EGFR (0.63) | EGFRERBB2ERBB4 | |
| SCHEMBL5564685 | 0.78 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664028-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026151-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |