SCHEMBL6017850

SCHEMBL6017850

CC(=O)Nc1ccc(S(=O)(=O)N[C@H]2C=C(C(=O)O)O[C@@H]([C@H](O)[C@H](O)CO)[C@@H]2NC(C)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NEU2 Q9Y3R4 9/20 0.60
NEU3 Q9UQ49 9/20 0.60
NEU4 Q8WWR8 9/20 0.60
NEU1 Q99519 7/20 0.60
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6017980 0.93 NEU2 (0.56) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6017987 0.91 NEU2 (0.64) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6018031 0.91 NEU2 (0.64) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6017787 0.91 NEU2 (0.64) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6017842 0.90 NEU1 (0.62) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6017838 0.90 NEU1 (0.62) NEU2NEU3NEU4NEU1LMNA
SCHEMBL7169885 0.90 NEU3 (0.61) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6018888 0.90 NEU3 (0.61) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6018104 0.90 NEU1 (0.61) NEU2NEU3NEU4NEU1LMNA
SCHEMBL6018200 0.90 NEU2 (0.61) NEU2NEU3NEU4NEU1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7045535-B2 Compounds useful for inhibiting paramyxovirus neuraminidase BIOCRYST PHARMACEUTICALS, INC. (US) 2006-05-16 US claimed
US-20030187063-A1 Compounds useful for inhibiting paramyxovirus neuraminidase BIOCRYST PHARMACEUTICALS, INC. 2003-10-02 US claimed
US-7045535-B2 Compounds useful for inhibiting paramyxovirus neuraminidase BIOCRYST PHARMACEUTICALS, INC. (US) 2006-05-16 US disclosed
US-20030187063-A1 Compounds useful for inhibiting paramyxovirus neuraminidase BIOCRYST PHARMACEUTICALS, INC. 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187063-A1 Compounds useful for inhibiting paramyxovirus neuraminidase SCN10A, NEU1, NEU4 NEU2 6/4885NEU3 4/4885NEU4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.