Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625675 | 0.83 | CRBN (0.44) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1625137 | 0.78 | TP53 (0.39) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL3951461 | 0.78 | CRBN (0.46) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL5520760 | 0.78 | TP53 (0.51) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1626169 | 0.77 | TP53 (0.50) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1625725 | 0.76 | TP53 (0.49) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL5520756 | 0.76 | CRBN (0.45) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1625133 | 0.76 | TP53 (0.49) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1627056 | 0.75 | SMN1; SMN2 (0.45) | CRBNTP53MAPTMEN1KMT2A | |
| SCHEMBL1626572 | 0.75 | SMN1; SMN2 (0.45) | CRBNTP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666480-A1 | Aryl or Heteroaryl Fused Imidazole Compounds as intermediates for Anti-Inflammatory And Analgesic Agents. | PFIZER PHARMACEUTICALS INC. (JP) | 2006-06-07 | — | — | EP | disclosed |