Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.71 |
| ▸ | SHBG | P04278 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.52 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018287 | 1.00 | CYP3A4 (0.77) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| SCHEMBL13752943 | 0.90 | CYP3A4 (0.70) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| SCHEMBL4110734 | 0.90 | CYP3A4 (0.70) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| SCHEMBL4110739 | 0.90 | CYP3A4 (0.70) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| Medrysone SCHEMBL29866793 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| Medrysone SCHEMBL12998543 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| Medrysone SCHEMBL3048275 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| Medrysone SCHEMBL4493 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| Medrysone SCHEMBL13054978 | 0.87 | CYP3A4 (1.00) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA | |
| SCHEMBL8668298 | 0.85 | SMN1; SMN2 (0.80) | CYP3A4CYP2C9HIF1ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018648-B2 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20050256051-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | THE POPULATION COUNCIL, INC. (US) | 2005-11-17 | — | — | US | disclosed |
| US-20050100586-A1 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2005-05-12 | — | — | US | disclosed |
| EP-1178806-B1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PF MEDICAMENT (FR) | 2004-09-01 | — | — | EP | disclosed |
| US-6767902-B2 | Androgen as a male contraceptive and non-contraceptive androgen replacement | THE POPULATION COUNCIL, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20040126418-A1 | Transdermal administration of MENT | THE POPULATION COUNCIL, INC. | 2004-07-01 | — | — | US | disclosed |
| US-20030096739-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | POPULATION COUNCIL, INC., THE | 2003-05-22 | — | — | US | disclosed |
| US-20020193359-A1 | Administering to a non-sterile male subject a predetermined amount of an androgen which is sufficient to render male subject reversibly sterile for a predetermined period of time | POPULATION COUNCIL, INC., THE | 2002-12-19 | — | — | US | disclosed |
| EP-1178806-A1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2002-02-13 | — | — | EP | disclosed |
| US-20020012694-A1 | TRANSDERMAL ADMINISTRATION OF MENT | POPULATION COUNCIL, INC., THE, A CORP. OF NY | 2002-01-31 | — | — | US | disclosed |
| WO-2000071133-A1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2000-11-30 | — | — | WO | disclosed |
| US-5342834-A | Administering testosterone derivatives | THE POPULATION COUNCIL, INC. (US) | 1994-08-30 | — | — | US | disclosed |