Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU2 | Q9Y3R4 | 7/20 | 0.60 |
| ▸ | NEU3 | Q9UQ49 | 7/20 | 0.60 |
| ▸ | NEU1 | Q99519 | 7/20 | 0.60 |
| ▸ | NEU4 | Q8WWR8 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018256 | 1.00 | NEU2 (0.60) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6017988 | 0.88 | NEU2 (0.67) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6017987 | 0.87 | NEU2 (0.64) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6017787 | 0.87 | NEU2 (0.64) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6018011 | 0.85 | NEU2 (0.52) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6018069 | 0.85 | NEU2 (0.64) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6017931 | 0.85 | NEU2 (0.64) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6018867 | 0.85 | NEU2 (0.69) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6017860 | 0.85 | NEU2 (0.69) | NEU2NEU3NEU1NEU4LMNA | |
| SCHEMBL6018250 | 0.84 | NEU2 (0.65) | NEU2NEU3NEU1NEU4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7045535-B2 | Compounds useful for inhibiting paramyxovirus neuraminidase | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | claimed |
| US-20030187063-A1 | Compounds useful for inhibiting paramyxovirus neuraminidase | BIOCRYST PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | claimed |
| US-7045535-B2 | Compounds useful for inhibiting paramyxovirus neuraminidase | BIOCRYST PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20030187063-A1 | Compounds useful for inhibiting paramyxovirus neuraminidase | BIOCRYST PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187063-A1 | Compounds useful for inhibiting paramyxovirus neuraminidase | SCN10A, NEU1, NEU4 | NEU2 6/4885NEU3 4/4885NEU1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.