Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018699 | 1.00 | LSS (0.51) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019511 | 0.99 | LSS (0.53) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019508 | 0.99 | LSS (0.53) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019832 | 0.89 | LSS (0.65) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019829 | 0.89 | LSS (0.65) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019147 | 0.88 | LSS (0.53) | LSSHRH3 | |
| SCHEMBL6019128 | 0.88 | LSS (0.64) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6019150 | 0.88 | LSS (0.53) | LSSHRH3 | |
| SCHEMBL6019125 | 0.88 | LSS (0.64) | LSSMAPTTP53KDM2BLMNA | |
| SCHEMBL6018729 | 0.86 | LSS (0.52) | LSSHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456171-B1 | SUBSTITUTED CYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-12-20 | — | — | EP | disclosed |