Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942713 | 0.81 | CYP19A1 (0.57) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL28534643 | 0.77 | CYP19A1 (0.57) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL28516089 | 0.75 | CYP19A1 (0.55) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL3271704 | 0.74 | CYP19A1 (0.54) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL30163675 | 0.74 | CYP19A1 (0.54) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL1137447 | 0.74 | CYP19A1 (0.59) | CYP19A1CTSVCTSLMAPTBRD4 | |
| SCHEMBL20536414 | 0.72 | MAPT (0.42) | CYP19A1MAPTBRD4MEN1KMT2A | |
| SCHEMBL6839572 | 0.71 | KCNJ11 (0.53) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL30064935 | 0.71 | KCNJ11 (0.53) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5579678 | 0.71 | CYP19A1 (0.53) | CYP19A1MAPTBRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |