Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282804 | 0.90 | DPP4 (0.47) | DPP4GRM5 | |
| SCHEMBL4952703 | 0.90 | DPP4 (0.47) | DPP4GRM5 | |
| SCHEMBL14282751 | 0.89 | DPP4 (0.65) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282802 | 0.89 | DPP4 (0.65) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282795 | 0.84 | DPP4 (0.46) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282794 | 0.83 | DPP4 (0.65) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282801 | 0.83 | DPP4 (0.44) | DPP4DPP8DPP9DPP7GRM5 | |
| SCHEMBL14282749 | 0.82 | DPP4 (0.58) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14282799 | 0.82 | DPP4 (0.58) | DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL4957955 | 0.80 | DPP4 (0.45) | DPP4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613304-A1 | DPP-IV INHIBITORS | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |