Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 12/20 | 0.73 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6019387 | 1.00 | LSS (0.73) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018776 | 0.97 | LSS (0.78) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018781 | 0.97 | LSS (0.78) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018706 | 0.96 | LSS (0.80) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018710 | 0.96 | LSS (0.80) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6020065 | 0.94 | LSS (0.67) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6020069 | 0.94 | LSS (0.67) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018402 | 0.90 | LSS (0.61) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018406 | 0.90 | LSS (0.61) | LSSHTR2CHTR2AHTR7HTR2B | |
| SCHEMBL6018391 | 0.88 | LSS (0.64) | LSSHTR2CHTR2AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456171-B1 | SUBSTITUTED CYCLOHEXANE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-12-20 | — | — | EP | disclosed |