Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6019467 | 0.98 | GBA1 (0.48) | GBA1ALDH1A1CNR2CNR1CYP19A1 | |
| SCHEMBL6020935 | 0.98 | GBA1 (0.48) | GBA1ALDH1A1CNR2CNR1CYP19A1 | |
| SCHEMBL6018789 | 0.95 | GBA1 (0.40) | GBA1ALDH1A1CYP19A1CYP1A1L3MBTL1 | |
| SCHEMBL6019260 | 0.89 | GBA1 (0.33) | GBA1 | |
| SCHEMBL6019489 | 0.82 | — | — | |
| SCHEMBL6019516 | 0.74 | MAPT (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL6018757 | 0.74 | CHRM2 (0.33) | — | |
| SCHEMBL6018783 | 0.73 | — | — | |
| SCHEMBL14145881 | 0.69 | GBA1 (0.44) | GBA1ALDH1A1CNR2CNR1CYP19A1 | |
| SCHEMBL8293296 | 0.68 | GBA1 (0.47) | GBA1ALDH1A1CNR2CNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060228387-A1 | Dihydronepetalactams and N-substituted derivatives thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228387-A1 | Dihydronepetalactams and N-substituted derivatives thereof | NOTCH4, NRDC, BPHL | GBA1 3079/4885ALDH1A1 2823/4885CNR2 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.