Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | IDE | P14735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366506 | 0.87 | CA1 (0.42) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL22284794 | 0.85 | CA1 (0.33) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL31397702 | 0.84 | TAAR1 (0.45) | CA1CA2CA4CA9TAAR1 | |
| Sulfuric Acid SCHEMBL28700686 | 0.83 | CA1 (0.46) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL10385184 | 0.83 | CA1 (0.42) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL29447126 | 0.83 | CA1 (0.39) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL83681 | 0.81 | CA1 (0.44) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL2638396 | 0.81 | TAAR1 (0.42) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL28480031 | 0.81 | TAAR1 (0.42) | CA1CA2CA4CA9TAAR1 | |
| SCHEMBL31006957 | 0.80 | CA1 (0.41) | CA1CA2CA4CA9TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270692-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270692-A1 | Chemical compounds | CCNI, MKI67, TP53 | CA1 4363/4885CA2 2154/4885CA4 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.