SCHEMBL60208

SCHEMBL60208

[Al+3].[O-]Cl.[O-]Cl.[O-]Cl.[S]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113210 0.89
SCHEMBL11351535 0.89 MAPK1 (0.60)
SCHEMBL6525104 0.80
SCHEMBL9333634 0.80 MAPK1 (0.50)
SCHEMBL8823329 0.80 MAPK1 (0.50)
Water SCHEMBL11748615 0.80 MAPK1 (0.50)
SCHEMBL9722667 0.80
Water SCHEMBL9429385 0.80
Water SCHEMBL5799361 0.80
SCHEMBL6525105 0.80 MAPK1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865232-B2 Method for treating ocular Demodex TISSUETECH, INC. (US) 2014-10-21 US disclosed
US-8865233-B2 Compositions and methods for treating Demodex infestations TISSUETECH, INC. (US) 2014-10-21 US disclosed
US-20130344128-A1 METHOD FOR TREATING OCULAR DEMODEX TISSUETECH, INC. (US) 2013-12-26 US disclosed
US-20130224272-A1 COMPOSITIONS AND METHODS FOR TREATING DEMODEX INFESTATIONS TISSUETECH, INC. (US) 2013-08-29 US disclosed
US-8455015-B2 Compositions and methods for treating Demodex infestations TISSUETECH, INC. (US) 2013-06-04 US disclosed
US-8440240-B2 Method for treating ocular demodex TISSUETECH, INC. (US) 2013-05-14 US disclosed
US-8128968-B2 Compositions and methods for treating Demodex infestations TISSUETECH, INC. (US) 2012-03-06 US disclosed
US-20120004320-A1 Method for Treating Ocular Demodex TissueTech,Inc. (US) 2012-01-05 US disclosed
US-20100273870-A1 COMPOSITIONS AND METHODS FOR TREATING DEMODEX INFESTATIONS TISSUETECH, INC. (US) 2010-10-28 US disclosed
EP-2192913-A2 COMPOSITIONS AND METHODS FOR TREATING DEMODEX INFESTATIONS TissueTech, Inc. (US) 2010-06-09 EP disclosed
US-20090214676-A1 METHOD FOR TREATING OCULAR DEMODEX TISSUETECH, INC. (US) 2009-08-27 US disclosed
WO-2009032773-A2 COMPOSITIONS AND METHODS FOR TREATING DEMODEX INFESTATIONS TISSUETECH, INC. (US) 2009-03-12 WO disclosed
US-20090061025-A1 COMPOSITIONS AND METHODS FOR TREATING DEMODEX INFESTATIONS TISSUETECH, INC. (US) 2009-03-05 US disclosed
WO-2006119174-A1 METHOD FOR TREATING OCULAR DEMODEX OCULAR SURFACE CENTER, P.A. (US) 2006-11-09 WO disclosed