Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358074 | 1.00 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22971752 | 0.98 | MEN1 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22960180 | 0.93 | TSHR (0.44) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8420927 | 0.86 | TSHR (0.39) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19098226 | 0.82 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL19098580 | 0.82 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14211509 | 0.82 | MEN1 (0.45) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL12257499 | 0.81 | LPAR3 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL12257497 | 0.81 | LPAR3 (0.41) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL1839694 | 0.80 | MEN1 (0.43) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261620-A2 | CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION | Roche Diagnostics Corporation (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2001057064-A2 | CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION | ROCHE DIAGNOSTICS CORPORATION (US) | 2001-08-09 | — | — | WO | claimed |
| EP-1648519-A2 | LIPID ENCAPSULATED INTERFERING RNA | Protiva Biotherapeutics Inc. (CA) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005007196-A2 | LIPID ENCAPSULATED INTERFERING RNA | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2005-01-27 | — | — | WO | disclosed |