Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901760 | 0.83 | RHEB (0.49) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL5901519 | 0.81 | KMT2A (0.45) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL5901935 | 0.81 | HPGD (0.51) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL4664782 | 0.80 | CYP11B1 (0.49) | SRD5A2SRD5A1MEN1RAB9AKMT2A | |
| SCHEMBL5901336 | 0.77 | PPIA (0.47) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL4662880 | 0.77 | BRD4 (0.50) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL4662895 | 0.77 | MEN1 (0.46) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL4664627 | 0.77 | KMT2A (0.42) | SRD5A2SRD5A1MEN1NPC1RAB9A | |
| SCHEMBL5173716 | 0.74 | MAPT (0.53) | MEN1NPC1RAB9AKMT2ARHEB | |
| SCHEMBL4753246 | 0.72 | HRH3 (0.40) | SRD5A2SRD5A1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |