Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.64 |
| ▸ | PDE4A | P27815 | 12/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548361 | 0.90 | PDE4B (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3541858 | 0.90 | PDE4B (0.73) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6021782 | 0.89 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3551823 | 0.89 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3549971 | 0.89 | PDE4B (0.72) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3545499 | 0.87 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3544326 | 0.87 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3549439 | 0.87 | PDE4B (0.62) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3552151 | 0.86 | PDE4B (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL3552313 | 0.86 | PDE4B (0.61) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663999-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES, LTD. (IN) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021515-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | disclosed |