Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476579 | 0.90 | TACR3 (0.75) | TACR3 | |
| SCHEMBL2477431 | 0.90 | TACR3 (0.75) | TACR3 | |
| SCHEMBL2473310 | 0.89 | TACR3 (0.74) | TACR3 | |
| SCHEMBL2480768 | 0.89 | TACR3 (0.74) | TACR3 | |
| SCHEMBL2475958 | 0.86 | TACR3 (0.75) | TACR3 | |
| SCHEMBL2473182 | 0.86 | TACR3 (0.75) | TACR3 | |
| SCHEMBL2482686 | 0.86 | TACR3 (0.82) | TACR3 | |
| SCHEMBL2479971 | 0.86 | TACR3 (0.82) | TACR3 | |
| SCHEMBL2473983 | 0.85 | TACR3 (0.71) | TACR3 | |
| SCHEMBL2476364 | 0.85 | TACR3 (0.71) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-A1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | H. Lundbeck A/S (DK) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005016884-A1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | H. LUNDBECK A/S (DK) | 2005-02-24 | — | — | WO | disclosed |