Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484083 | 0.91 | KMT2A (0.62) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL6475948 | 0.88 | KMT2A (0.62) | KMT2ALMNA | |
| SCHEMBL6023108 | 0.88 | CA1 (0.54) | KMT2AMEN1CA1CA2LMNA | |
| SCHEMBL6023639 | 0.88 | — | — | |
| SCHEMBL6478319 | 0.88 | KMT2A (0.62) | KMT2APOLBLMNA | |
| SCHEMBL6022541 | 0.85 | CA1 (0.57) | KMT2AMEN1CA1CA2LMNA | |
| SCHEMBL6476553 | 0.84 | KMT2A (0.55) | KMT2AMEN1LMNA | |
| SCHEMBL6023589 | 0.84 | KMT2A (0.60) | KMT2AMEN1LMNA | |
| SCHEMBL3370380 | 0.83 | KMT2A (0.54) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL6023518 | 0.83 | KMT2A (0.55) | KMT2AMEN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641794-A1 | NOVEL PYRROLODIHYDROISOQUINOLINES USEFUL IN THE TREATMENT OF CANCER | ALTANA Pharma AG (DE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005003130-A1 | NOVEL PYRROLODIHYDROISOQUINOLINES USEFUL IN THE TREATMENT OF CANCER | ALTANA PHARMA AG (DE) | 2005-01-13 | — | — | WO | disclosed |