Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 13/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024146 | 0.89 | PDE2A (0.41) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6023700 | 0.88 | PDE2A (0.45) | PDE2ARNASEH1KDM4EATMPOLB | |
| SCHEMBL6023361 | 0.88 | PDE2A (0.45) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6023710 | 0.87 | PDE2A (0.47) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6023281 | 0.81 | KDM4E (0.41) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6024603 | 0.78 | PDE2A (0.42) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6023988 | 0.78 | CCNE2 (0.41) | PDE2ARNASEH1KDM4EATMCCNE2 | |
| SCHEMBL6023204 | 0.74 | PDE2A (0.51) | PDE2ARNASEH1 | |
| SCHEMBL6024102 | 0.74 | PDE2A (0.47) | PDE2ARNASEH1MAPTKDM4EALDH1A1 | |
| SCHEMBL6023972 | 0.73 | PDE2A (0.52) | PDE2ARNASEH1POLBCCNE2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | ALTANA PHARMA AG (DE) | 2006-05-18 | — | — | US | disclosed |
| EP-1601675-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA Pharma AG (DE) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004089953-A1 | PURIN-6-ONE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106037-A1 | Purin-6-one-derivatives | PDE4B, PDE4A, PDE2A | PDE2A 3/4885RNASEH1 450/4885MAPT 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.