SCHEMBL602386

SCHEMBL602386

O=C(O)c1ccccc1CCl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.59
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.53
TP53 P04637 1/20 0.51
HTT P42858 1/20 0.51
HMGB1 P09429 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HPGD P15428 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3624217 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL28805448 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL27345540 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
Hydrogen Sulfide SCHEMBL27518474 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL27495555 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL27334154 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
Water SCHEMBL28844415 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL27690026 0.98 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRTP53
SCHEMBL27619745 0.96 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRTP53
Methyl Alcohol SCHEMBL27864731 0.96 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119822722-A Anti-cracking plant fiber concrete and preparation method thereof 中建四局第六建设有限公司 2025-04-15 CN claimed
CN-119735514-A Preparation method of aminomethylbenzoic acid 江西道仕化学有限公司 2025-04-01 CN claimed
CN-221514505-U Production device of p-chloromethyl benzoic acid 云南衡楚药业有限公司 2024-08-13 CN claimed
CN-221287872-U Processing recovery unit of p-chloromethyl benzoic acid 云南衡楚药业有限公司 2024-07-09 CN claimed
EP-3169403-B9 ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES PROTAGONIST THERAPEUTICS INC (US) 2024-07-03 EP claimed
US-20240199700-A1 ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES PROTAGONIST THERAPEUTICS INC (US) 2024-06-20 US claimed
EP-4378536-A2 ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES Protagonist Therapeutics, Inc. (US) 2024-06-05 EP claimed
CN-118063472-A Imidazo [3,4-d ] pyrimidine compound and synthetic method and application thereof 河北大学 2024-05-24 CN claimed
EP-3169403-B1 ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES PROTAGONIST THERAPEUTICS INC (US) 2024-02-14 EP claimed
US-20230416252-A1 PROCESS TOWARD THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE JANSSEN PHARMACEUTICA NV (BE) 2023-12-28 US claimed
CN-101328319-A Water-soluble bridged ring polymethine 3H-indole cyanine dyes ultrasonic synthetic method UNIV YANSHAN (CN) 2008-12-24 CN claimed
CN-101328318-A Water-soluble linear polymethine 3H-indole cyanine dyes ultrasonic synthetic method UNIV YANSHAN (CN) 2008-12-24 CN claimed
CN-101012182-A Azo monomer and polymer with third order non-linear optical property UNIV SOOCHOW (CN) 2007-08-08 CN claimed
CN-1975552-A Third order non-linear optical material monomer, its polymer and production UNIV SUZHOU (CN) 2007-06-06 CN claimed
CN-1907948-A Preparation method of 4-chloromethyl benzoic acid t-butyl ester UNIV TONGJI (CN) 2007-02-07 CN claimed
CN-1282695-C Flame retardant compositions CIBA SC HOLDING AG (CH) 2006-11-01 CN claimed
CN-1705705-A Flame retardant composition CIBA SC HOLDING AG (CH) 2005-12-07 CN claimed
EP-0884096-B1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use KOCH MEMBRANE SYSTEMS INC (US) 2005-09-14 EP claimed
CN-1498244-A Flame retardant compositions �������⻯ѧƷ�ع����޹�˾ 2004-05-19 CN claimed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199700-A1 ORAL PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY BOWEL DISEASES IL23R, IL1RN, VIP FOLH1 481/4885ALDH1A1 4662/4885ALOX15 917/4885
US-20230416252-A1 PROCESS TOWARD THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE CYP1B1, AZI2, TET1 FOLH1 2526/4885ALDH1A1 206/4885ALOX15 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.