Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124348 | 0.88 | NR1H2 (0.69) | NR1H2NR1H3 | |
| SCHEMBL27673920 | 0.87 | NR1H2 (0.88) | NR1H2NR1H3 | |
| SCHEMBL1124262 | 0.87 | NR1H2 (0.79) | NR1H2NR1H3 | |
| SCHEMBL1124681 | 0.86 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1124692 | 0.84 | NR1H2 (0.95) | NR1H2NR1H3 | |
| SCHEMBL1125604 | 0.84 | NR1H2 (0.64) | NR1H2NR1H3 | |
| SCHEMBL1125005 | 0.84 | NR1H2 (0.64) | NR1H2NR1H3 | |
| SCHEMBL1124818 | 0.84 | NR1H2 (0.64) | NR1H2NR1H3 | |
| SCHEMBL1125328 | 0.83 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL1124382 | 0.83 | NR1H2 (0.63) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692111-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | Wyeth, A Corporation of the State of Delaware (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058834-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | WYETH (US) | 2005-06-30 | — | — | WO | disclosed |