Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 19/20 | 0.62 |
| ▸ | OXTR | P30559 | 12/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566944 | 0.97 | AVPR1A (0.65) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL6024946 | 0.92 | AVPR1A (0.54) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2128605 | 0.88 | AVPR1A (0.56) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL6024950 | 0.88 | AVPR1A (0.56) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2129412 | 0.88 | AVPR1A (0.54) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2128826 | 0.83 | AVPR1A (0.52) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18944423 | 0.83 | AVPR1A (0.52) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL18917267 | 0.82 | AVPR1A (0.57) | AVPR1AOXTRAVPR2CHRM2CHRM4 | |
| SCHEMBL2128928 | 0.82 | AVPR1A (0.52) | AVPR1AOXTRAVPR2 | |
| SCHEMBL5567012 | 0.81 | AVPR1A (0.63) | AVPR1AOXTRAVPR2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660501-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023812-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2005-03-17 | — | — | WO | disclosed |