Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.63 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.63 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312515 | 0.91 | TLR7 (0.60) | TLR7TLR8 | |
| SCHEMBL1614839 | 0.87 | TLR7 (0.61) | TLR7TLR8NUDT1LMNAPOLB | |
| SCHEMBL1490402 | 0.86 | TLR7 (0.65) | TLR7TLR8NUDT1LMNAPOLB | |
| SCHEMBL6723566 | 0.86 | TLR7 (0.65) | TLR7TLR8NUDT1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL4519914 | 0.85 | TLR7 (0.64) | TLR7TLR8NUDT1LMNAPOLB | |
| SCHEMBL1490683 | 0.85 | TLR7 (0.61) | TLR7TLR8NUDT1LMNAPOLB | |
| SCHEMBL1490534 | 0.85 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL6723972 | 0.85 | TLR7 (0.63) | TLR7TLR8 | |
| SCHEMBL893024 | 0.84 | TLR7 (0.74) | TLR7TLR8NUDT1LMNAPOLB | |
| SCHEMBL5453031 | 0.84 | TLR7 (0.62) | TLR7TLR8NUDT1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1617871-A2 | DELIVERY OF IMMUNE RESPONSE MODIFIER COMPOUNDS USING METAL-CONTAINING PARTICULATE SUPPORT MATERIALS | 3M Innovative Properties Company (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1615665-A2 | DELIVERY OF IMMUNE RESPONSE MODIFIER COMPOUNDS | 3M Innovative Properties Company (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004108072-A2 | DELIVERY OF IMMUNE RESPONSE MODIFIER COMPOUNDS USING METAL-CONTAINING PARTICULATE SUPPORT MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004091500-A2 | DELIVERY OF IMMUNE RESPONSE MODIFIER COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-10-28 | — | — | WO | disclosed |