Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409160 | 1.00 | CNR1 (0.48) | CNR1CNR2LMNATP53HTT | |
| SCHEMBL3321804 | 0.87 | CNR1 (0.48) | CNR1CNR2TRPV1SIRT2SIRT1 | |
| SCHEMBL3321810 | 0.87 | CNR1 (0.48) | CNR1CNR2TRPV1SIRT2SIRT1 | |
| SCHEMBL7479500 | 0.82 | HTR2C (0.42) | CNR1CNR2LMNATP53HTT | |
| SCHEMBL3322619 | 0.81 | TRPV1 (0.41) | KCNE1KCNQ1TRPV1KDM1A | |
| SCHEMBL6024969 | 0.81 | BACE1 (0.37) | CNR1CNR2LMNAHTTTRPV1 | |
| SCHEMBL3322624 | 0.81 | TRPV1 (0.41) | KCNE1KCNQ1TRPV1KDM1A | |
| Hydrochloric Acid SCHEMBL6561142 | 0.81 | HTR2C (0.41) | CNR1CNR2LMNATP53HTT | |
| SCHEMBL6025054 | 0.81 | BACE1 (0.37) | CNR1CNR2LMNAHTTTRPV1 | |
| SCHEMBL6024931 | 0.81 | TRPV1 (0.41) | KCNE1KCNQ1TRPV1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716141-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005075463-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | UNIVERSITE DE LIEGE (BE) | 2005-08-18 | — | — | WO | disclosed |