Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025164 | 1.00 | SIRT2 (0.61) | SIRT2SIRT1TRPV1ALDH1A1MAPT | |
| SCHEMBL6024957 | 0.90 | SIRT2 (0.62) | SIRT2SIRT1TRPV1ALDH1A1MAPT | |
| SCHEMBL6024372 | 0.78 | TRPV1 (0.50) | SIRT2SIRT1TRPV1 | |
| SCHEMBL9529658 | 0.75 | SIRT2 (0.52) | SIRT2SIRT1ABCC9 | |
| SCHEMBL9272118 | 0.73 | SIRT2 (0.72) | SIRT2SIRT1TRPV1 | |
| SCHEMBL31371256 | 0.73 | SIRT2 (1.00) | SIRT2SIRT1TRPV1 | |
| SCHEMBL6027651 | 0.71 | SIRT2 (0.47) | SIRT2SIRT1TRPV1 | |
| SCHEMBL4257277 | 0.71 | CNR1 (0.54) | SIRT2SIRT1TRPV1 | |
| SCHEMBL9690460 | 0.71 | SIRT2 (0.54) | SIRT2SIRT1TRPV1ABCC9 | |
| SCHEMBL9690471 | 0.71 | SIRT2 (0.54) | SIRT2SIRT1TRPV1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716141-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2006-11-02 | — | — | EP | claimed |
| WO-2005075463-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | UNIVERSITE DE LIEGE (BE) | 2005-08-18 | — | — | WO | claimed |
| EP-1716141-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005075463-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | UNIVERSITE DE LIEGE (BE) | 2005-08-18 | — | — | WO | disclosed |