Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380707 | 1.00 | C5AR1 (0.37) | C5AR1KDM1AMAPK14EGFRERBB2 | |
| SCHEMBL4392462 | 1.00 | C5AR1 (0.37) | C5AR1KDM1AMAPK14EGFRERBB2 | |
| SCHEMBL4381387 | 0.91 | MAPK14 (0.35) | MAPK14L3MBTL1TDP1MAPTMAPK1 | |
| SCHEMBL4384038 | 0.91 | MAPK14 (0.35) | MAPK14L3MBTL1TDP1MAPTMAPK1 | |
| SCHEMBL4385084 | 0.91 | MAPK14 (0.35) | MAPK14L3MBTL1TDP1MAPTMAPK1 | |
| SCHEMBL4380968 | 0.89 | AR (0.36) | KDM1AMAPK14HTR1ASLC6A2SLC6A4 | |
| SCHEMBL4386419 | 0.89 | ESR1 (0.36) | L3MBTL1TDP1MAPTMAPK1 | |
| SCHEMBL4382854 | 0.89 | MAPT (0.34) | MAPK14LRRK2L3MBTL1TDP1MAPT | |
| SCHEMBL4386470 | 0.89 | AR (0.36) | KDM1AMAPK14HTR1ASLC6A2SLC6A4 | |
| SCHEMBL4386156 | 0.89 | ESR1 (0.36) | L3MBTL1TDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704856-A1 | HSP90 FAMILY PROTEIN INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-27 | — | — | EP | disclosed |