SCHEMBL6025854

SCHEMBL6025854

CCCCc1ccc(S(=O)(=O)O/N=C(\C(=O)OCC)c2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
CNR2 P34972 1/20 0.41
CA2 P00918 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
AKT1 P31749 2/20 0.39
IRS1 P35568 2/20 0.39
GAB1 Q13480 2/20 0.39
POLB P06746 1/20 0.39
RARB P10826 1/20 0.39
TSHR P16473 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PLK1 P53350 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 2/20 0.38
THRA P10827 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6025345 1.00 ENPP1 (0.43) ENPP1GAAKMT2ACNR2CA2
SCHEMBL6024564 0.89 KMT2A (0.51) GAAKMT2ACA2SMN1; SMN2POLB
SCHEMBL6024561 0.89 KMT2A (0.51) GAAKMT2ACA2SMN1; SMN2POLB
SCHEMBL6025267 0.89 CNR2 (0.46) ENPP1CNR2CA2SMN1; SMN2RARB
SCHEMBL6025271 0.89 CNR2 (0.46) ENPP1CNR2CA2SMN1; SMN2RARB
SCHEMBL6024675 0.89 KMT2A (0.49) ENPP1GAAKMT2ACA2SMN1; SMN2
SCHEMBL6025617 0.89 KMT2A (0.49) ENPP1GAAKMT2ACA2SMN1; SMN2
SCHEMBL6025465 0.86 GAA (0.43) ENPP1GAAKMT2ASMN1; SMN2POLB
SCHEMBL6025463 0.86 GAA (0.43) ENPP1GAAKMT2ASMN1; SMN2POLB
SCHEMBL6025112 0.84 KMT2A (0.46) GAAKMT2ASMN1; SMN2NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed
JP-2002538241-A 2002-11-12 JP claimed
EP-1163553-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS Ciba SC Holding AG (CH) 2001-12-19 EP claimed
WO-2000052530-A1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-09-08 WO claimed
EP-1163553-B1 OXIME DERIVATIVES AND THE USE THEREOF AS PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2006-06-14 EP disclosed
US-6806024-B1 MIXTURES OF ADDITION POLYMERS AND ACTIVATORS COMPRISING NITROGEN COMPOUNDS, USED AS SUBSTRATE COATINGS FOR COLOR FILTERS CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-19 US disclosed