Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026717 | 1.00 | ESR1 (0.56) | ESR1NPC1CA12CA1CA2 | |
| SCHEMBL4420391 | 0.92 | ESR1 (0.58) | ESR1NPC1CA12CA1CA2 | |
| SCHEMBL6026813 | 0.87 | ESR1 (0.53) | ESR1NPC1ALOX5AKR1C4AKR1C3 | |
| SCHEMBL679252 | 0.87 | ESR1 (0.53) | ESR1NPC1CA12CA1CA2 | |
| SCHEMBL6792765 | 0.85 | ESR1 (0.71) | ESR1NPC1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9678194 | 0.85 | ESR1 (0.71) | ESR1NPC1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9678186 | 0.85 | ESR1 (0.71) | ESR1NPC1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9679699 | 0.85 | ESR1 (0.71) | ESR1NPC1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL11700483 | 0.85 | ESR1 (0.71) | ESR1NPC1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7138691 | 0.85 | ESR1 (0.52) | ESR1NPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034098-B2 | POlyimide, polyamide; liquid crystals, opticsoptics | ROLIC AG (CH) | 2006-04-25 | — | — | US | disclosed |
| EP-1368411-B1 | PHOTOACTIVE POLYMER | ROLIC AG (CH) | 2005-07-06 | — | — | EP | disclosed |
| US-20040185215-A1 | Photoactive polymer based on polyimides, polyamic acids and esters characterised in that it contains as a side-chain a dendritic block incorporating photoactive groups at its surface; use as orientation layers for liquid crystals and in the construction of unstructured and structured optical elements | ROLIC AG (CH) | 2004-09-23 | — | — | US | disclosed |
| EP-1229066-A1 | Photoactive polymer | Rolic AG (CH) | 2002-08-07 | — | — | EP | disclosed |