Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 10/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CPS1 | P31327 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | ACTR2 | P61160 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4589081 | 1.00 | CCR1 (0.61) | CCR1MAOBGAAKMT2ACPS1 | |
| SCHEMBL4589092 | 1.00 | CCR1 (0.61) | CCR1MAOBGAAKMT2ACPS1 | |
| SCHEMBL4589085 | 1.00 | CCR1 (0.61) | CCR1MAOBGAAKMT2ACPS1 | |
| SCHEMBL5056215 | 0.93 | CCR1 (0.64) | CCR1KMT2ACPS1MAPK11MAPK14 | |
| SCHEMBL5056217 | 0.93 | CCR1 (0.64) | CCR1KMT2ACPS1MAPK11MAPK14 | |
| SCHEMBL5056222 | 0.93 | CCR1 (0.64) | CCR1KMT2ACPS1MAPK11MAPK14 | |
| SCHEMBL5055826 | 0.92 | CCR1 (0.61) | CCR1KMT2AMAPK11MAPK14MAPK13 | |
| SCHEMBL5055828 | 0.92 | CCR1 (0.61) | CCR1KMT2AMAPK11MAPK14MAPK13 | |
| SCHEMBL5055825 | 0.92 | CCR1 (0.61) | CCR1KMT2AMAPK11MAPK14MAPK13 | |
| SCHEMBL5064277 | 0.92 | CCR1 (0.63) | CCR1MAOBKMT2AMAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713483-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | Schering Aktiengesellschaft (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005077372-A1 | CHEMOKINE INHIBITING PIPERAZINE DERIVATIVES AND THEIR USE TO TREAT MULTIPLE MYELOMA | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | WO | disclosed |