Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815838 | 0.92 | CALCRL (0.49) | CALCRL | |
| SCHEMBL1198384 | 0.92 | CALCRL (0.49) | CALCRL | |
| SCHEMBL13929780 | 0.84 | CALCRL (0.51) | CALCRL | |
| SCHEMBL1198546 | 0.83 | CALCRL (0.44) | CALCRL | |
| SCHEMBL2899143 | 0.82 | CALCRL (0.60) | CALCRL | |
| SCHEMBL13929777 | 0.81 | CALCRL (0.48) | CALCRL | |
| SCHEMBL1197428 | 0.80 | CALCRL (0.47) | CALCRL | |
| SCHEMBL13798878 | 0.79 | CALCRL (0.47) | CALCRL | |
| SCHEMBL13929806 | 0.79 | CALCRL (0.53) | CALCRL | |
| SCHEMBL3066255 | 0.78 | CALCRL (0.60) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638969-A2 | CGRP RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004092166-A2 | CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2004-10-28 | — | — | WO | disclosed |