SCHEMBL6027334

SCHEMBL6027334

[CH2]C(C=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.49
SLC1A2 P43004 2/20 0.49
SLC1A1 P43005 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TSHR P16473 2/20 0.44
IDO1 P14902 1/20 0.41
AGXT P21549 1/20 0.40
CCNB2 O95067 1/20 0.40
CDK1 P06493 1/20 0.40
CDK4 P11802 1/20 0.40
CCNB1 P14635 1/20 0.40
CCND1 P24385 1/20 0.40
CCNB3 Q8WWL7 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7116036 0.81 TSHR (0.46) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL8081797 0.78 TSHR (0.52) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL2703824 0.78 TSHR (0.52) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL4588952 0.78 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL7501665 0.78 SLC1A3 (0.51) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL6172748 0.78 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL6239311 0.78 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL20871816 0.77 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL6108993 0.77 EPHX1 (0.50) SLC1A3SLC1A2SLC1A1KMT2AMEN1
SCHEMBL19917416 0.77 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994022-A BECOMES SOLUBLE IN ALKALI DEVELOPING SOLUTION BY ACTION OF AN ACID JSR CORPORATION (JP) 1999-11-30 US claimed
US-7115358-B2 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2006-10-03 US disclosed
US-20050266361-A1 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. 2005-12-01 US disclosed
WO-1991000854-A1 N,N'-DICARBOXYMETHYL, N,N'-DIAMINOCARBONYLMETHYL-DIAMINOALKANE DERIVATIVES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-01-24 WO disclosed
EP-0408384-A1 N,N'-dicarboxymethyl, N,N'-dicarbamoylmethyl diaminoalkane derivatives and their use in pharmaceutical compositions. BTG INTERNATIONAL LIMITED (GB) 1991-01-16 EP disclosed
EP-0053816-B1 1-SULFO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1988-05-04 EP disclosed