SCHEMBL6028153

SCHEMBL6028153

CC(C)(C)OC(=O)n1cccc1[Sn](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
BCHE P06276 1/20 0.43
BUB1 O43683 1/20 0.40
PIK3R1 P27986 1/20 0.37
PIK3CA P42336 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.35
GPR119 Q8TDV5 4/20 0.35
TNK2 Q07912 1/20 0.34
MAPK1 P28482 1/20 0.34
HTR6 P50406 1/20 0.33
ABCB1 P08183 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163016 0.81 HSP90AA1 (0.47) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL8546440 0.78 BCHE (0.40) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL4916320 0.77 HSP90AA1 (0.47) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL15417736 0.77 HSP90AA1 (0.47) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL24914436 0.76 HSP90AA1 (0.52) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL8264796 0.76 HSP90AA1 (0.46) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL19204908 0.76 HSP90AA1 (0.46) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL7361304 0.76 HSP90AA1 (0.49) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL2616414 0.76 HSP90AA1 (0.46) HSP90AA1HSP90AB1BCHEBUB1PIK3R1
SCHEMBL13180192 0.76 HSP90AA1 (0.46) HSP90AA1HSP90AB1BCHEBUB1PIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015301-B2 (Electro)luminescent polymer-acceptor system comprising a polymer and an acceptor for transferring excitation energy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-03-21 US disclosed
US-20040225106-A1 (Electro)luminescent polymer-acceptor system comprising a polymer and an acceptor for transferring excitation energy KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-11-11 US disclosed
EP-1399979-A2 (ELECTRO)LUMINESCENT POLYMER-ACCEPTOR SYSTEM COMPRISING A POLYMER AND AN ACCEPTOR FOR TRANSFERRING EXCITATION ENERGY Koninklijke Philips Electronics N.V. (NL) 2004-03-24 EP disclosed
WO-2002100975-A2 (ELECTRO)LUMINESCENT DEVICE WITH AN ORGANIC DYE AS AN ACCEPTOR KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2002-12-19 WO disclosed
WO-2002101846-A2 (ELECTRO)LUMINESCENT POLYMER-ACCEPTOR SYSTEM COMPRISING A POLYMER AND AN ACCEPTOR FOR TRANSFERRING EXCITATION ENERGY KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2002-12-19 WO disclosed